Manufacturer Potassium tert-butoxide for sell
Potassium tert-butoxide is the chemical compound with the formula K+(CH3)3CO−. This colourless solid is a strong base (pKa of conjugate acid around 17), which is useful in organic synthesis. It exists as a tetrameric cubane-type cluster. It is often seen written in chemical literature as potassium t-butoxide. The compound is often depicted as a salt, and it often behaves as such, but it is not ionized in solution.
CAS Number: 865-47-4
ECHA InfoCard: 100.011.583
PubChem CID: 70077
Chemical formula: C4H9KO
Molar mass: 112.21 g mol−1
Melting point: 256 °C (493 °F; 529 K)
Solubility in diethyl ether: 4.34 g/100 g (25-26 °C)
Solubility in Hexane: 0.27 g/100 g (25-26 °C)
Solubility in Toluene: 2.27 g/100 g (25-26 °C)
Solubility in THF: 25.00 g/100 g (25-26 °C)
The tert-butoxide species is itself useful as a strong, non-nucleophilic base in organic chemistry. It is not as strong as amide bases, e.g. lithium diisopropylamide, but stronger than potassium hydroxide. Its steric bulk inhibits the group from participating in nucleophilic addition, such as in a Williamson ether synthesis or an SN2 reaction. Substrates that are deprotonated by potassium t-butoxide include terminal acetylenes and active methylene compounds. It is useful in dehydrohalogenation reactions.
Potassium tert-butoxide catalyzes the reaction of hydrosilanes and heterocyclic compounds to give the silyl derivatives, with release of H2.