Manufacturer Potassium tert-butoxide for sell


Potassium tert-butoxide is the chemical compound with the formula K+(CH3)3CO−. This colourless solid is a strong base (pKa of conjugate acid around 17), which is useful in organic synthesis. It exists as a tetrameric cubane-type cluster. It is often seen written in chemical literature as potassium t-butoxide. The compound is often depicted as a salt, and it often behaves as such, but it is not ionized in solution.

CAS Number: 865-47-4 
ECHA InfoCard:    100.011.583
PubChem CID: 70077

Chemical formula: C4H9KO
Molar mass:    112.21 g mol−1
Appearance:    solid
Melting point:    256 °C (493 °F; 529 K)
Solubility in diethyl ether:    4.34 g/100 g (25-26 °C)
Solubility in Hexane:    0.27 g/100 g (25-26 °C) 
Solubility in Toluene:    2.27 g/100 g (25-26 °C) 
Solubility in THF:    25.00 g/100 g (25-26 °C) 

The tert-butoxide species is itself useful as a strong, non-nucleophilic base in organic chemistry.[4] It is not as strong as amide bases, e.g. lithium diisopropylamide, but stronger than potassium hydroxide. Its steric bulk inhibits the group from participating in nucleophilic addition, such as in a Williamson ether synthesis or an SN2 reaction. Substrates that are deprotonated by potassium t-butoxide include terminal acetylenes and active methylene compounds. It is useful in dehydrohalogenation reactions.

Potassium tert-butoxide catalyzes the reaction of hydrosilanes and heterocyclic compounds to give the silyl derivatives, with release of H2.